Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 10/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.38 |
| ▸ | FGF2 | P09038 | 1/20 | 0.35 |
| ▸ | MDK | P21741 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | BDNF | P23560 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511906 | 0.98 | TLR4 (0.41) | TLR4LY96FGF2MDKHDAC1 | |
| SCHEMBL6801798 | 0.98 | TLR4 (0.41) | TLR4LY96FGF2 | |
| SCHEMBL8431664 | 0.82 | TLR4 (0.45) | TLR4LY96HDAC1HDAC2 | |
| SCHEMBL9513498 | 0.81 | SMPD1 (0.42) | — | |
| SCHEMBL6807592 | 0.81 | SMPD1 (0.41) | TLR4LY96 | |
| SCHEMBL10417944 | 0.79 | TLR4 (0.48) | TLR4LY96 | |
| SCHEMBL9511533 | 0.79 | TLR4 (0.48) | TLR4LY96 | |
| SCHEMBL9511499 | 0.77 | SMPD1 (0.40) | TLR4LY96 | |
| SCHEMBL9514279 | 0.76 | SMPD1 (0.42) | — | |
| SCHEMBL9512993 | 0.75 | HDAC1 (0.34) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | claimed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |