Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 6/20 | 0.56 |
| ▸ | TOP1 | P11387 | 4/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512148 | 0.96 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9513032 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9509708 | 0.87 | TOP1 (0.52) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9512154 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9509737 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9560217 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9513066 | 0.78 | TOP2A (0.59) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL30114800 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9461276 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10668369 | 0.75 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563733-A1 | Use of 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxacin-6-carboxylic acid- and esters for the manufacture of a medicament for the treatment of viral diseases | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |