SCHEMBL9513491

SCHEMBL9513491

COc1ccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513001 0.91
SCHEMBL9358577 0.86 HRH2 (0.60)
SCHEMBL10673169 0.85
SCHEMBL10671942 0.85
SCHEMBL9513497 0.85 HRH2 (0.71)
SCHEMBL9513535 0.85
Dalcotidine SCHEMBL29395522 0.84 HRH2 (0.70)
Dalcotidine SCHEMBL1815082 0.84 HRH2 (0.70)
SCHEMBL9515110 0.83
SCHEMBL10527928 0.83 HRH2 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1139563-A None JP disclosed
EP-0302422-B1 Urea derivatives KYORIN SEIYAKU KK (JP) 1993-12-08 EP disclosed
US-5077302-A Antiulcer agents KYORIN PHARMACEUTICAL CO., LTD. (JP) 1991-12-31 US disclosed
US-4952591-A HISTAMINE H2-ANTAGONISTS KYORIN PHARMACEUTICAL CO., LTD. (JP) 1990-08-28 US disclosed
JP-H01139563-A UREA DERIVATIVE KYORIN PHARMACEUT CO LTD 1989-06-01 JP disclosed