SCHEMBL9513499

SCHEMBL9513499

C[Si](C)(C)OS(=O)(=O)C(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708332 0.83 CA1 (0.31)
SCHEMBL28527 0.75 CA1 (0.32)
SCHEMBL5565770 0.73 CA1 (0.30)
SCHEMBL21148404 0.73 USP2 (0.32)
Bromide SCHEMBL4662499 0.73 CA1 (0.30)
SCHEMBL23227942 0.73 CA1 (0.30)
Hydrochloric Acid SCHEMBL9085192 0.73 CA1 (0.30)
SCHEMBL4365549 0.72
SCHEMBL8459925 0.71
SCHEMBL10712135 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0143323-B1 PROCESS FOR AN ANTHRACYCLINE DERIVATIVE, AND AN ANTHRACYCLINONE DERIVATIVE USEFUL FOR THE PROCESS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-10-26 EP claimed
US-4564674-A Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-01-14 US claimed
EP-0143323-A2 Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-06-05 EP claimed
EP-0246068-B1 Process for the manufacture of cephalosporin derivatives ICI PLC (GB) 1993-12-08 EP disclosed
US-4939250-A Process for preparation of β-lactam derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-03 US disclosed
EP-0143323-B1 PROCESS FOR AN ANTHRACYCLINE DERIVATIVE, AND AN ANTHRACYCLINONE DERIVATIVE USEFUL FOR THE PROCESS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-10-26 EP disclosed
EP-0246068-A2 Process for the manufacture of cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-19 EP disclosed
US-4564674-A Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-01-14 US disclosed
EP-0143323-A2 Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-06-05 EP disclosed