SCHEMBL9514072

SCHEMBL9514072

FOP(Oc1ccccc1C1CCCCC1)Oc1ccccc1C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 2/20 0.48
HTR1D P28221 2/20 0.40
HTR1B P28222 2/20 0.40
ADRA2A P08913 3/20 0.40
ADRA2B P18089 2/20 0.40
ADRA2C P18825 2/20 0.40
HTR2C P28335 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HTR1A P08908 7/20 0.38
SLC6A2 P23975 7/20 0.38
SLC6A4 P31645 7/20 0.38
SLC6A3 Q01959 6/20 0.38
USP2 O75604 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CHRM1 P11229 1/20 0.37
CYP2C9 P11712 1/20 0.37
DRD1 P21728 1/20 0.37
TBXA2R P21731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413823 1.00 PTGDR2 (0.48) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL130364 0.90 PTGDR2 (0.53) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL9514060 0.83 PTGDR2 (0.50) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL10413822 0.83 PTGDR2 (0.50) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL5086150 0.82 PTGDR2 (0.50) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL9512474 0.81 FEN1 (0.36) PTGDR2HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL6656290 0.79 PTGDR2 (0.54) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL4901024 0.79 PTGDR2 (0.54) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL11044865 0.77 PTGDR2 (0.49) PTGDR2HTR1DHTR1BADRA2AADRA2B
SCHEMBL10413316 0.76 PTGDR2 (0.39) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301355-B1 Aqueous aryl fluorophosphite suspension ETHYL CORP (US) 1993-12-29 EP disclosed
US-4867907-A POLYMER STABILIZERS ETHYL CORPORATION (US) 1989-09-19 US disclosed
EP-0301355-A2 Aqueous aryl fluorophosphite suspension ETHYL CORPORATION (US) 1989-02-01 EP disclosed