SCHEMBL9514342

SCHEMBL9514342

C=C(C)C(=O)OC(CC)OC(=O)/C=C\C(=O)OC(CC)OC(=O)C(=C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.38
TSHR P16473 4/20 0.37
ALDH1A1 P00352 3/20 0.35
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9157560 1.00 HCAR2 (0.38) HCAR2TSHRALDH1A1THRBATM
SCHEMBL9157590 1.00 HCAR2 (0.38) HCAR2TSHRALDH1A1THRBATM
SCHEMBL9514354 0.93 HCAR2 (0.50) HCAR2TSHRALDH1A1THRB
SCHEMBL601418 0.88 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL9850076 0.87 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL9162961 0.86 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL5068871 0.86 TSHR (0.43) TSHRALDH1A1THRB
Methacrylic Acid SCHEMBL6545289 0.82 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL8968857 0.82 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL10824502 0.81 GLA (0.44) HCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325038-B1 Surface priming composition for proteinaceous substrates, method of making and using same OPI PROD INC (US) 1993-11-03 EP disclosed
EP-0325038-A2 Surface priming composition for proteinaceous substrates, method of making and using same OPI PRODUCTS, INC. (US) 1989-07-26 EP disclosed