Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675515 | 0.89 | MAPT (0.65) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19029271 | 0.85 | HDAC6 (0.81) | MAPTHDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL19945200 | 0.84 | HDAC6 (0.71) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9820132 | 0.84 | MAPT (0.60) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5638115 | 0.84 | MAPT (0.70) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13254495 | 0.81 | KDM4E (0.59) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28381958 | 0.81 | HDAC6 (0.61) | MAPTHDAC6SMN1; SMN2TP53HDAC3 | |
| SCHEMBL28382537 | 0.81 | HDAC6 (0.61) | MAPTHDAC6SMN1; SMN2TP53HDAC3 | |
| SCHEMBL28380321 | 0.81 | MAPT (0.50) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9289255 | 0.81 | MAPT (0.56) | MAPTHDAC6SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5017458-A | — | — | None | — | — | JP | disclosed |
| JP-H0517458-A | AROMATIC COMPOUND AND ITS PRODUCTION | IDEMITSU KOSAN CO LTD | 1993-01-26 | — | — | JP | disclosed |