Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514559 | 1.00 | SNCA (0.76) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL6116675 | 0.84 | SNCA (0.53) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL6116681 | 0.84 | SNCA (0.53) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL14571513 | 0.83 | SNCA (0.74) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL5584495 | 0.83 | SNCA (0.74) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL30767226 | 0.82 | SNCA (0.72) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL9515558 | 0.78 | SNCA (0.60) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL9515572 | 0.78 | SNCA (0.60) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL10619184 | 0.77 | SNCA (0.65) | SNCAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL1242918 | 0.77 | MEN1 (0.67) | SNCAMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |