Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514122 | 0.99 | LTB4R2 (0.52) | LTB4R2TSHRHSD17B10BRS3AGTR1 | |
| SCHEMBL11753978 | 0.96 | LTB4R2 (0.53) | LTB4R2TSHRHSD17B10BRS3AGTR1 | |
| SCHEMBL8676465 | 0.91 | LTB4R2 (0.50) | LTB4R2BRS3PPARG | |
| SCHEMBL8678446 | 0.83 | TSHR (0.46) | LTB4R2TSHRHSD17B10RARBPTPN11 | |
| SCHEMBL10536375 | 0.82 | RARB (0.59) | LTB4R2BRS3RARB | |
| SCHEMBL8678448 | 0.82 | RARB (0.47) | LTB4R2AGTR1AGTR2RARBPTPN11 | |
| SCHEMBL8678080 | 0.79 | MPL (0.45) | LTB4R2TSHRHSD17B10BRS3RARB | |
| SCHEMBL2744074 | 0.78 | LTB4R2 (0.46) | LTB4R2TSHRBRS3 | |
| SCHEMBL8678083 | 0.78 | LTB4R2 (0.43) | LTB4R2BRS3RARBPTPN11 | |
| SCHEMBL27297604 | 0.78 | PLK1 (0.50) | TSHRRARBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187768-B1 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS | FERGASON JAMES L (US) | 1993-11-03 | — | — | EP | disclosed |
| US-5130828-A | Liquid crystal temperature sensor and materials | MANCHESTER R&D PARTNERSHIP (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0187768-A4 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. | FERGASON JAMES L | 1989-03-09 | — | — | EP | disclosed |
| EP-0187768-A1 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. | FERGASON JAMES L | 1986-07-23 | — | — | EP | disclosed |
| WO-1985005467-A1 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS | FERGASON JAMES L | 1985-12-05 | — | — | WO | disclosed |