Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PTGFR | P43088 | 2/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515758 | 1.00 | PTGER3 (0.43) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL2388955 | 0.87 | ESR1 (0.47) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL6855197 | 0.84 | CA1 (0.47) | PTGER3PTGER2PTGER1TBXA2RPTGDR | |
| SCHEMBL2865033 | 0.84 | CA1 (0.47) | PTGER3PTGER2PTGER1TBXA2RPTGDR | |
| SCHEMBL3183824 | 0.81 | PTGER3 (0.48) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL2391055 | 0.80 | AKR1C3 (0.44) | PTGER3PTGER2PTGER1PTGER4SMN1; SMN2 | |
| SCHEMBL2393450 | 0.79 | ESR1 (0.46) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL3954647 | 0.79 | PTGER3 (0.49) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL6678566 | 0.79 | ESR1 (0.48) | PTGER3PTGER2PTGER1PTGER4CA1 | |
| SCHEMBL6668620 | 0.79 | ESR1 (0.48) | PTGER3PTGER2PTGER1PTGER4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |