Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 17/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516024 | 1.00 | CACNA1F (0.46) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520512 | 0.84 | CACNA1F (0.67) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520545 | 0.84 | CACNA1F (0.67) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520526 | 0.84 | CACNA1F (0.67) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9521000 | 0.83 | CACNA1F (0.66) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL10595210 | 0.83 | CACNA1F (0.66) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9521017 | 0.83 | CACNA1F (0.66) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9521010 | 0.83 | CACNA1F (0.66) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9521387 | 0.82 | CACNA1F (0.51) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9521466 | 0.79 | POLB (0.58) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5025162-A | — | — | None | — | — | JP | disclosed |
| JP-H0525162-A | QUINOLONE DERIVATIVE AND ITS PRODUCTION | SHIONOGI & CO LTD | 1993-02-02 | — | — | JP | disclosed |
| JP-H00525162-A | — | — | 0001-01-01 | — | — | JP | disclosed |