Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388112 | 1.00 | MAPT (0.61) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL14935499 | 0.87 | MAPT (0.69) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL9978289 | 0.87 | MAPT (0.69) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL11049170 | 0.87 | MAPT (0.69) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL11299049 | 0.85 | MAPT (0.67) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL11296000 | 0.85 | MAPT (0.67) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL5440784 | 0.83 | SOS1 (0.71) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL5440780 | 0.83 | SOS1 (0.71) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL1531429 | 0.82 | MAPT (0.62) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL1531427 | 0.82 | MAPT (0.62) | MAPTSOS1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430001-B1 | Process for preparing benzaldehydes | BAYER AG (DE) | 1993-12-22 | — | — | EP | claimed |
| US-5082976-A | PROCESS FOR THE PREPARATION OF BENZALDEHYDES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | claimed |
| US-5082976-A | PROCESS FOR THE PREPARATION OF BENZALDEHYDES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4595765-A | Process for preparing 5,6-dihydroxyindole | CLAIROL INCORPORATED (US) | 1986-06-17 | — | — | US | disclosed |
| US-4454337-A | Semicarbazide intermediates for preparing 4-substituted indoles | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4394514-A | Processes for preparing 4-substituted indoles | SMITHKLINE BECKMAN CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| US-3976639-A | Intermediates for indoles | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976639-A | Intermediates for indoles | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |