SCHEMBL9516175

SCHEMBL9516175

CO[Si](CCCN1CCCCC1C(C)C)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9520234 0.80 CYP1A2 (0.46) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL2113723 0.79 GBA1 (0.34) HRH3
SCHEMBL19684428 0.77 S1PR1 (0.39) CYP2D6TSHRHRH3
SCHEMBL9517635 0.77 MAPK1 (0.44) CYP1A2CYP2D6TSHR
SCHEMBL2113722 0.76 HRH3 (0.34) HRH3
SCHEMBL2113628 0.74 HRH3 (0.37) HRH3
SCHEMBL16980418 0.73 KCNK3 (0.36) HRH3
SCHEMBL24422019 0.73 GBA2 (0.34) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL2116396 0.71 GBA1 (0.34)
SCHEMBL24272787 0.70 HRH3 (0.37) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP disclosed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US disclosed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP disclosed