Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519350 | 0.87 | KAT2B (0.70) | KAT2BMAPTKMT2ALMNAPKM | |
| SCHEMBL112161 | 0.87 | KAT2B (0.70) | KAT2BMAPTKMT2ALMNAPKM | |
| SCHEMBL20419963 | 0.87 | KAT2B (0.70) | KAT2BMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20419976 | 0.87 | KAT2B (0.60) | KAT2BMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL22126311 | 0.85 | KAT2B (0.56) | KAT2BMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6218547 | 0.85 | KAT2B (0.74) | KAT2BMAPTKMT2ALMNAPKM | |
| SCHEMBL26913572 | 0.84 | KAT2B (0.65) | KAT2BMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6214461 | 0.84 | KAT2B (0.73) | KAT2BMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6220073 | 0.82 | KAT2B (0.71) | KAT2BMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL29868082 | 0.82 | KMT2A (0.71) | MAPTKMT2ASMN1; SMN2LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391662-B1 | Nitroaniline dyes with a cyano substituent group | BRISTOL MYERS SQUIBB CO (US) | 1993-10-27 | — | — | EP | claimed |
| US-5024673-A | Colorfast direct yellow hair dye | CLAIROL INCORPORATED (US) | 1991-06-18 | — | — | US | claimed |
| US-4980158-A | HAIR DYES; PHOTOSTABILITY, WASHFASTNESS | CLAIROL INCORPORATED (US) | 1990-12-25 | — | — | US | claimed |
| EP-0391662-A1 | Nitroaniline dyes with a cyano substituent group | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | claimed |
| EP-0391662-B1 | Nitroaniline dyes with a cyano substituent group | BRISTOL MYERS SQUIBB CO (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5024673-A | Colorfast direct yellow hair dye | CLAIROL INCORPORATED (US) | 1991-06-18 | — | — | US | disclosed |
| US-4980158-A | HAIR DYES; PHOTOSTABILITY, WASHFASTNESS | CLAIROL INCORPORATED (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0391662-A1 | Nitroaniline dyes with a cyano substituent group | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | disclosed |