Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515594 | 0.97 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9514295 | 0.96 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9515161 | 0.96 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9517924 | 0.96 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9516406 | 0.96 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9515380 | 0.96 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9514442 | 0.93 | PPARA (0.33) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL10784967 | 0.83 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9512656 | 0.81 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL10346722 | 0.80 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381728-B1 | DIFLUOROMETHYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |