Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934626 | 0.95 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL935218 | 0.95 | HCRTR1 (0.69) | HCRTR1HCRTR2 | |
| SCHEMBL951318 | 0.93 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL954975 | 0.92 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL1076769 | 0.90 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL934571 | 0.89 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL935275 | 0.87 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL935121 | 0.87 | CYP3A4 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL934699 | 0.87 | CYP3A4 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL934698 | 0.87 | CYP3A4 (0.62) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454252-A1 | SPIRO AMINO COMPOUNDS SUITABLE FOR THE TREATMENT OF INTER ALIA SLEEP DISORDERS AND DRUG ADDICTION | Rottapharm S.p.A. (IT) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006960-A1 | SPIRO AMINO COMPOUNDS SUITABLE FOR THE TREATMENT OF INTER ALIA SLEEP DISORDERS AND DRUG ADDICTION | ROTTAPHARM S.P.A. (IT) | 2011-01-20 | — | — | WO | disclosed |