SCHEMBL9516737

SCHEMBL9516737

CC[C@H]1CC[C@H](c2ccccc2C2(OC(F)F)C=CC(C(=O)O)C=C2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337719 0.96 FFAR1 (0.33) FFAR1
SCHEMBL9517894 0.92 CYP2C9 (0.37)
SCHEMBL9514174 0.90 MAPT (0.32)
SCHEMBL9516779 0.89 CYSLTR2 (0.35)
SCHEMBL9514070 0.88 CYSLTR2 (0.36) S1PR5
SCHEMBL9515658 0.88 CYSLTR2 (0.36) S1PR5
SCHEMBL9516403 0.88 CYSLTR2 (0.36) S1PR5
SCHEMBL9516412 0.88 CYSLTR2 (0.36) S1PR5
SCHEMBL9518034 0.88 CYSLTR2 (0.36) S1PR5
SCHEMBL9514170 0.88 FFAR1 (0.32) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0381728-B1 DIFLUOROMETHYL COMPOUNDS MERCK PATENT GMBH (DE) 1993-12-08 EP disclosed