Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 10/20 | 0.42 |
| ▸ | HTR2B | P41595 | 10/20 | 0.42 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516824 | 1.00 | KDM1A (0.43) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL21236291 | 0.84 | KDM1A (0.60) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL4893904 | 0.79 | HTR2C (0.66) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL2826045 | 0.79 | HTR2C (0.66) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL2826042 | 0.79 | HTR2C (0.66) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL7959436 | 0.76 | HTR2C (0.68) | KDM1AHTR2CHTR2BHTR2ASLC5A1 | |
| SCHEMBL7959439 | 0.76 | HTR2C (0.68) | KDM1AHTR2CHTR2BHTR2ASLC5A1 | |
| SCHEMBL9518913 | 0.75 | SLC6A2 (0.40) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| SCHEMBL9518907 | 0.75 | SLC6A2 (0.40) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| SCHEMBL9580445 | 0.74 | SLC6A2 (0.49) | HTR2CHTR2BHTR2AKCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |