Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.90 |
| ▸ | CA4 | P22748 | 4/20 | 0.61 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7055857 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL11768103 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL3714201 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL28859803 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL28849631 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL7055856 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL153505 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL10529780 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1964006 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1332530 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551419-A | anti-settling ink based on ink-jet stability of printer | ZHUHAI COLORPRO ELECTRONIC TECH CO LTD | 2019-12-10 | — | — | CN | claimed |
| US-5178167-A | Cigarettes and fuels | R. J. REYNOLDS TOBACCO COMPANY (US) | 1993-01-12 | — | — | US | claimed |
| CN-110551419-A | anti-settling ink based on ink-jet stability of printer | ZHUHAI COLORPRO ELECTRONIC TECH CO LTD | 2019-12-10 | — | — | CN | disclosed |
| EP-3308647-A1 | AGROCHEMICAL COMPOSITIONS FOR REDUCING AGROCHEMICAL RESIDUES | Rotam Agrochem International Co., Ltd (CN) | 2018-04-18 | — | — | EP | disclosed |
| EP-2816895-B1 | AGROCHEMICAL COMPOSITIONS FOR REDUCING AGROCHEMICAL RESIDUES | ROTAM AGROCHEM INT CO LTD (CN) | 2017-12-27 | — | — | EP | disclosed |
| CN-107430236-A | POLARIZING PLATE AND METHOD FOR PRODUCING SAME | 日东电工株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-107430235-A | Polarizer, polarizing plate and method for producing polarizer | 日东电工株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-107206761-A | Multilayer film | 株式会社可乐丽 | 2017-09-26 | — | — | CN | disclosed |
| US-20130123741-A1 | FLEXIBLE STERILE BAG CONTAINING PHARMACEUTICAL PRODUCTS AND DILUANT SEPARATELY AND METHOD OF MAKING THE SAME | GALENOVA INC (CA) | 2013-05-16 | — | — | US | disclosed |
| EP-0384798-B1 | LIMULUS TEST-POSITIVE PLANT GLYCOLIPID, AND METHOD OF STIMULATING THE IMMUNO SYSTEM OF AN ANIMAL | Soma, Gen-Ichiro (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5071968-A | Lightfastness, compatibility with other dyes | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-4739066-A | HYPOTENSIVE AGENTS, ANGIOTENSIN INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4638000-A | HYPOTENSIVES, ANGIOTENSIN INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-01-20 | — | — | US | disclosed |
| EP-0156455-A2 | Condensed seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-3976636-A | Process and compounds | THE UPJOHN COMPANY (US) | 1976-08-24 | — | — | US | disclosed |