Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226244 | 0.75 | PARP1 (0.50) | — | |
| SCHEMBL31302083 | 0.72 | CYP2D6 (0.43) | HDAC4 | |
| SCHEMBL10339218 | 0.72 | AKR1B1 (0.46) | — | |
| SCHEMBL19617106 | 0.71 | — | — | |
| Benzene SCHEMBL15265833 | 0.70 | AKR1B1 (0.50) | — | |
| SCHEMBL9187362 | 0.70 | — | — | |
| SCHEMBL9190615 | 0.70 | — | — | |
| SCHEMBL23933927 | 0.70 | HDAC4 (0.49) | HDAC4 | |
| SCHEMBL28854800 | 0.69 | AKR1B1 (0.47) | HDAC4 | |
| SCHEMBL7141107 | 0.69 | HDAC4 (0.65) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552386-A1 | 2-Amino-3 or 6-methoxycyclohexyl amide derivatives | WARNER-LAMBERT COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| EP-0380063-B1 | 1,2-CYCLOHEXYLAMINOARYL AMIDES USEFUL AS ANALGESIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-07-21 | — | — | EP | disclosed |
| US-5051428-A | 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics | WARNER-LAMBERT COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| US-5019588-A | Nonhabit-forming analgeiscs | WARNER-LAMBERT COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0372466-A2 | 2-Amino-4 or 5-methoxycyclohexyl amides useful as analgesics | WARNER-LAMBERT COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| US-4906655-A | Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4463013-A | Oxygen substituted amino-cyclohexyl-benzeneacetamides and -benzamides as water diuretic drugs | THE UPJOHN COMPANY (US) | 1984-07-31 | — | — | US | disclosed |