Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517171 | 0.99 | KMT2A (0.49) | KMT2AMEN1P4HTMCYSLTR1ALDH1A1 | |
| SCHEMBL9518004 | 0.99 | KMT2A (0.49) | KMT2AMEN1P4HTMCYSLTR1ALDH1A1 | |
| SCHEMBL9516960 | 0.99 | KMT2A (0.49) | KMT2AMEN1P4HTMCYSLTR1ALDH1A1 | |
| SCHEMBL9515737 | 0.94 | NPC1 (0.49) | KMT2AMEN1CYSLTR1MAPTRAB9A | |
| SCHEMBL9519339 | 0.94 | NPC1 (0.49) | KMT2AMEN1CYSLTR1MAPTRAB9A | |
| SCHEMBL9515824 | 0.91 | PPARA (0.46) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL9515526 | 0.91 | MAPT (0.47) | KMT2AMEN1CYSLTR1MAPTLMNA | |
| SCHEMBL9517102 | 0.91 | NPC1 (0.49) | KMT2AMEN1P4HTMCYSLTR1MAPT | |
| SCHEMBL9515761 | 0.91 | CA1 (0.53) | KMT2AALDH1A1MAPTLMNACNR2 | |
| SCHEMBL9517289 | 0.91 | MAPT (0.47) | KMT2AMEN1CYSLTR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |