SCHEMBL9517329

SCHEMBL9517329

COC(=O)CSCCSCC(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
HSD17B10 Q99714 6/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
KDM1A O60341 1/20 0.42
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
ALOX15 P16050 2/20 0.38
MAPK1 P28482 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
POLB P06746 2/20 0.37
TP53 P04637 2/20 0.36
MAPT P10636 2/20 0.36
TET2 Q6N021 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15282914 0.90 KDM1A (0.47) TSHRHSD17B10MGAMGAASI
SCHEMBL27233181 0.89 TSHR (0.39) TSHRHSD17B10MGAMGAASI
SCHEMBL11056301 0.88 TSHR (0.53) TSHRHSD17B10MGAMGAASI
SCHEMBL5017557 0.87
SCHEMBL1845437 0.87 TSHR (0.55) TSHRHSD17B10MGAMGAASI
SCHEMBL774678 0.87
SCHEMBL27233219 0.87 TSHR (0.37) TSHRHSD17B10MGAMGAASI
SCHEMBL30888816 0.86 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL2859838 0.85
SCHEMBL8435869 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8980077-B2 Plating bath and method ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2015-03-17 US disclosed
US-20130256145-A1 PLATING BATH AND METHOD DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-03 US disclosed
EP-0345847-B1 PROCESS FOR THE PREPARATION OF POLYMERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-04 EP disclosed
EP-0345847-A1 Process for the preparation of polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-12-13 EP disclosed
US-4174428-A CYCLIC TETRAAMINES WITH PENDANT AMINOALKYLS AND POLYSTYRENE WITH THE TETRAAMINE BONDED THERETO Tabushi, Iwao (JP) 1979-11-13 US disclosed