Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196700 | 1.00 | NPC1 (0.48) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL6178354 | 0.97 | NPC1 (0.44) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL12073502 | 0.84 | NPC1 (0.39) | NPC1EPHX1 | |
| SCHEMBL11874994 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL19188607 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL11876461 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL2739873 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL11882737 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL11882714 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL3504567 | 0.83 | NPC1 (0.41) | NPC1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464045-B1 | DISCONTINUOUS PROCESS FOR CONDUCTING A HETEROGENEOUSLY CATALYSED REACTION AND INSTALLATION FOR HETEROGENEOUSLY CATALYSED MANUFACTURE OF PRODUCTS | HENKEL KGAA (DE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0464045-A1 | DISCONTINUOUS PROCESS FOR CONDUCTING A HETEROGENEOUSLY CATALYSED REACTION AND INSTALLATION FOR HETEROGENEOUSLY CATALYSED MANUFACTURE OF PRODUCTS. | HENKEL KGAA (DE) | 1992-01-08 | — | — | EP | disclosed |
| WO-1990011114-A1 | DISCONTINUOUS PROCESS FOR CONDUCTING A HETEROGENEOUSLY CATALYSED REACTION AND INSTALLATION FOR HETEROGENEOUSLY CATALYSED MANUFACTURE OF PRODUCTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-10-04 | — | — | WO | disclosed |