Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 4/20 | 0.45 |
| ▸ | HMGCR | P04035 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892587 | 0.91 | — | — | |
| SCHEMBL4688591 | 0.83 | — | — | |
| SCHEMBL3626347 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL2123036 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL26251491 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL28743000 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL10404839 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL11045543 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL5375334 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 | |
| SCHEMBL26624468 | 0.82 | PTPN7 (0.67) | PTPN7HMGCRCYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384842-B1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| EP-0384842-A1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1990-08-29 | — | — | EP | disclosed |