Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221652 | 1.00 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL9995136 | 0.98 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL16937424 | 0.96 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL9766284 | 0.93 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL7066521 | 0.93 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL9227581 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL6849095 | 0.92 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL11583553 | 0.91 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL10797039 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4PRSS1 | |
| SCHEMBL1823127 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526520-A1 | MILDNESS ADDITIVES FOR SKIN CLEANSING COMPOSITIONS. | MINNESOTA MINING & MFG (US) | 1993-02-10 | — | — | EP | disclosed |
| WO-1991016037-A1 | MILDNESS ADDITIVES FOR SKIN CLEANSING COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |