Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294560 | 0.84 | MAPK1 (0.54) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9518838 | 0.82 | MAPK1 (0.56) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2265406 | 0.82 | MAPK1 (0.51) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13081115 | 0.77 | KDM4E (0.49) | MAPK1KDM4EHSD17B10NPSR1KMT2A | |
| SCHEMBL12295364 | 0.77 | MAPK1 (0.75) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12294561 | 0.76 | KDM4E (0.58) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13144236 | 0.75 | KDM4E (0.50) | MAPK1SMN1; SMN2KDM4EHSD17B10NPSR1 | |
| SCHEMBL6491851 | 0.75 | KDM4E (0.50) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18629834 | 0.75 | MAPK1 (0.50) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23655844 | 0.74 | SMN1; SMN2 (0.46) | MAPK1SMN1; SMN2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |