SCHEMBL9518715

SCHEMBL9518715

BrCCOCCOCCOCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
NAAA Q02083 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
IDO1 P14902 1/20 0.43
TRPA1 O75762 1/20 0.42
LTA4H P09960 1/20 0.42
AGXT P21549 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
HTT P42858 1/20 0.40
HRH4 Q9H3N8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16437098 1.00 TSHR (0.58) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL9516494 1.00 TSHR (0.58) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL1594369 1.00 TSHR (0.58) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL20120433 1.00 TSHR (0.58) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL146520 0.96 TSHR (0.64) TSHRNAAASMN1; SMN2ALDH1A1TDP1
SCHEMBL11544338 0.93 TSHR (0.61) TSHRNAAASMN1; SMN2ALDH1A1TDP1
SCHEMBL24773684 0.92 TSHR (0.54) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL15140027 0.89 TSHR (0.47) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL15145980 0.89 TSHR (0.47) TSHRNAAASMN1; SMN2NPC1MAPT
SCHEMBL4608747 0.89 TSHR (0.74) TSHRNAAASMN1; SMN2TDP1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
WO-2025049820-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-03-06 WO disclosed
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof LIU, MIAO (CN) 2023-08-10 US disclosed
US-10941115-B2 Kinase inhibitors OXULAR ACQUISITIONS LIMITED (GB) 2021-03-09 US disclosed
US-20190330155-A1 KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2019-10-31 US disclosed
US-10392346-B2 Kinase inhibitors TOPIVERT PHARMA LIMITED (GB) 2019-08-27 US disclosed
US-10125100-B2 Kinase inhibitors RESPIVERT LIMITED 2018-11-13 US disclosed
US-20180319748-A1 KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2018-11-08 US disclosed
US-20180235992-A1 IMMUNOTHERAPIES FOR MALIGNANT, NEURODEGENERATIVE AND DEMYELINATING DISEASES BY THE USE OF TARGETED NANOCARRIERS RODOS BIOTARGET GMBH (DE) 2018-08-23 US disclosed
EP-3328367-A1 IMMUNOTHERAPIES FOR MALIGNANT, NEURODEGENERATIVE AND DEMYELINATING DISEASES BY THE USE OF TARGETED NANOCARRIERS Rodos BioTarget GmbH (DE) 2018-06-06 EP disclosed
WO-2017017148-A1 IMMUNOTHERAPIES FOR MALIGNANT, NEURODEGENERATIVE AND DEMYELINATING DISEASES BY THE USE OF TARGETED NANOCARRIERS RODOS BIOTARGET GMBH (DE) 2017-02-02 WO disclosed
US-20160102059-A1 KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2016-04-14 US disclosed
WO-2016051187-A1 DIARYL UREA DERIVATIVES AS P38 KINASE INHIBITORS RESPIVERT LIMITED (GB) 2016-04-07 WO disclosed
EP-0341409-B1 Platinum (II) complexes, their preparation and use as antitumour agents BOEHRINGER MANNHEIM ITALIA (IT) 1993-12-29 EP disclosed
EP-0287042-B1 2-SULPHINYL-ACETYL-1,3-THIAZOLIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1992-09-16 EP disclosed
EP-0415939-A1 PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1991-03-13 EP disclosed
EP-0341409-A1 Platinum (II) complexes, their preparation and use as antitumour agents BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-11-15 EP disclosed
WO-1989009218-A1 PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-10-05 WO disclosed
US-4849437-A 2-sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-07-18 US disclosed
EP-0287042-A1 2-Sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1988-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180235992-A1 IMMUNOTHERAPIES FOR MALIGNANT, NEURODEGENERATIVE AND DEMYELINATING DISEASES BY THE USE OF TARGETED NANOCARRIERS MAG, MSR1, CD47 TSHR 862/4885NAAA 3546/4885SMN1; SMN2 638/4885
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 TSHR 70/4885NAAA 3147/4885SMN1; SMN2 2865/4885
US-20180319748-A1 KINASE INHIBITORS LYN, SYK, BTK TSHR 2315/4885NAAA 4844/4885SMN1; SMN2 4346/4885
US-10125100-B2 Kinase inhibitors SYK, LYN, SRC TSHR 1681/4885NAAA 4589/4885SMN1; SMN2 3903/4885
US-20190330155-A1 KINASE INHIBITORS SYK, LYN, BTK TSHR 1763/4885NAAA 4349/4885SMN1; SMN2 4531/4885
US-10941115-B2 Kinase inhibitors SYK, LYN, BTK TSHR 1763/4885NAAA 4349/4885SMN1; SMN2 4531/4885
US-20160102059-A1 KINASE INHIBITORS SYK, LYN, BTK TSHR 1571/4885NAAA 4396/4885SMN1; SMN2 4459/4885
US-10392346-B2 Kinase inhibitors LYN, SYK, BTK TSHR 2315/4885NAAA 4844/4885SMN1; SMN2 4346/4885
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof VIP, GHITM, MYCBP TSHR 1587/4885NAAA 3882/4885SMN1; SMN2 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.