Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10539038 | 0.99 | APOBEC3A (0.32) | — | |
| SCHEMBL2103689 | 0.80 | KDM4E (0.30) | — | |
| SCHEMBL2103288 | 0.79 | MEN1 (0.41) | — | |
| SCHEMBL9521424 | 0.76 | AOC3 (0.32) | — | |
| SCHEMBL4629061 | 0.73 | PDE10A (0.32) | — | |
| SCHEMBL9518604 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL11049042 | 0.71 | HTR2C (0.46) | CHRM2 | |
| SCHEMBL1145591 | 0.70 | — | — | |
| SCHEMBL6212313 | 0.69 | AOC3 (0.53) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL2103538 | 0.69 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |