Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.70 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 16/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520194 | 1.00 | CACNA1F (0.70) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520203 | 1.00 | CACNA1F (0.70) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL10595818 | 0.99 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9520115 | 0.99 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL10596367 | 0.99 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9520121 | 0.99 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9520103 | 0.99 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520487 | 0.93 | POLB (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520390 | 0.93 | POLB (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9520477 | 0.93 | POLB (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347851-B1 | Quinolonecarboxylic acids | SHIONOGI & CO (JP) | 1993-11-10 | — | — | EP | claimed |
| EP-0347851-A1 | Quinolonecarboxylic acids | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | claimed |
| EP-0347851-B1 | Quinolonecarboxylic acids | SHIONOGI & CO (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-5106854-A | Bactericides | SHIONOGI & CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0347851-A1 | Quinolonecarboxylic acids | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | disclosed |