Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8229886 | 0.82 | MAPK1 (0.69) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9517362 | 0.78 | MAPK1 (0.71) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL952278 | 0.73 | MAPK1 (1.00) | MAPK1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL10595807 | 0.73 | DAO (0.49) | MAPK1NPC1SMN1; SMN2TSHRFFAR1 | |
| SCHEMBL9517850 | 0.73 | PPARG (0.45) | MAPK1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL20181585 | 0.70 | MAPK1 (0.48) | MAPK1NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL8812585 | 0.70 | MAPK1 (0.72) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22627475 | 0.70 | MAPK1 (0.60) | MAPK1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL31214441 | 0.69 | GAA (0.46) | MAPK1NPC1HTTSMN1; SMN2TSHR | |
| SCHEMBL2827309 | 0.69 | MAPK1 (0.71) | MAPK1NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |