Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 18/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519586 | 0.93 | NPY5R (0.45) | NPY5RCYP3A4CYP2D6OPRK1UTS2R | |
| SCHEMBL9519772 | 0.89 | NPY5R (0.61) | NPY5RCYP3A4CYP2D6OPRK1UTS2R | |
| SCHEMBL9521409 | 0.82 | CHRM5 (0.40) | NPY5RCYP3A4CYP2D6OPRK1UTS2R | |
| SCHEMBL9522609 | 0.82 | CHRM5 (0.38) | NPY5RCYP3A4CYP2D6OPRK1UTS2R | |
| SCHEMBL9519612 | 0.82 | NPY5R (0.51) | NPY5RNPY1R | |
| SCHEMBL9520865 | 0.81 | NPY5R (0.59) | NPY5RCYP3A4CYP2D6OPRK1UTS2R | |
| SCHEMBL9519595 | 0.76 | NPY5R (0.62) | NPY5RNPY1R | |
| SCHEMBL11594943 | 0.76 | NPY5R (0.62) | NPY5RNPY1R | |
| SCHEMBL10595801 | 0.75 | NPY5R (0.65) | NPY5RNPY1R | |
| SCHEMBL9520205 | 0.75 | NPY5R (0.61) | NPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288973-B1 | BENZOTHIAZOLINONE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | Fujisawa Astra Ltd. (JP) | 1993-01-13 | — | — | EP | claimed |
| US-4879301-A | Antiallergic and antiinflammatory benzothiazolinone derivatives | HOEI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | claimed |
| EP-0288973-A2 | Benzothiazolinone derivatives, their production and pharmaceutical composition | Fujisawa Astra Ltd. (JP) | 1988-11-02 | — | — | EP | claimed |
| EP-0288973-B1 | BENZOTHIAZOLINONE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | Fujisawa Astra Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |
| US-4879301-A | Antiallergic and antiinflammatory benzothiazolinone derivatives | HOEI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0288973-A2 | Benzothiazolinone derivatives, their production and pharmaceutical composition | Fujisawa Astra Ltd. (JP) | 1988-11-02 | — | — | EP | disclosed |