Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380480 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| SCHEMBL9521570 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| SCHEMBL19548104 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9ATSHRRECQL | |
| SCHEMBL17753933 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| Hydrochloric Acid SCHEMBL19639681 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| SCHEMBL29606541 | 0.74 | KDM4E (0.71) | SMN1; SMN2HTTKDM4EMEN1LMNA | |
| SCHEMBL24101616 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| SCHEMBL19658782 | 0.73 | TAF1 (0.54) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| SCHEMBL19639675 | 0.73 | TAF1 (0.54) | SMN1; SMN2HTTNPC1RAB9AGLA | |
| SCHEMBL14970141 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTNPC1RAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | claimed |
| EP-0301474-B1 | NEW CYSTEINE DERIVATIVES HAVING EXPECTORANT ACTIVITY | MAGIS FARMACEUTICI S.P.A. (IT) | 1993-09-29 | — | — | EP | claimed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | claimed |
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |