Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519978 | 0.66 | NOTUM (0.36) | CNR2ALDH1A1CNR1 | |
| SCHEMBL10391799 | 0.66 | CNR2 (0.33) | CNR2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL10391800 | 0.66 | CNR2 (0.38) | GRM2CNR2PDE5APDE4APDE4B | |
| SCHEMBL9519739 | 0.64 | CNR2 (0.32) | RORARORCRORBCNR2CNR1 | |
| SCHEMBL1628564 | 0.53 | SMN1; SMN2 (0.78) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12035535 | 0.53 | CHRM5 (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19117334 | 0.52 | CCR1 (0.37) | GRM2CNR2ALDH1A1 | |
| SCHEMBL23571170 | 0.51 | SMN1; SMN2 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19566355 | 0.51 | CYP3A4 (0.64) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23674849 | 0.51 | GRM2 (0.33) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |
| EP-0300898-A1 | Pyrethrinoid derivatives containing an N-heterocycle, processes and intermediates for their preparation, their use as pesticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-01-25 | — | — | EP | disclosed |