Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523037 | 0.83 | PPARG (0.46) | ALDH1A1KDM4ELMNAMAPTPPARG | |
| SCHEMBL5795341 | 0.83 | KDM4E (0.54) | KDM4EPPARGPPARAPPARDFFAR1 | |
| SCHEMBL9520639 | 0.82 | PIM1 (0.43) | RAB9A | |
| SCHEMBL9520645 | 0.82 | PIM1 (0.43) | RAB9A | |
| SCHEMBL10480772 | 0.82 | KDM4E (0.53) | KDM4EPPARGPPARAPPARDFFAR1 | |
| SCHEMBL10480771 | 0.81 | KDM4E (0.52) | KDM4EPPARGPPARAPPARDFFAR1 | |
| SCHEMBL9521218 | 0.78 | PPARA (0.49) | MAPTPPARGPPARAPPARD | |
| SCHEMBL9520936 | 0.78 | PPARG (0.43) | ALDH1A1KDM4EMAPTPPARGPPARA | |
| SCHEMBL9523122 | 0.75 | PPARG (0.44) | ALDH1A1MAPTPPARGPPARAFFAR1 | |
| SCHEMBL9787633 | 0.74 | HDAC1 (0.44) | ALDH1A1KDM4EGAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332332-B1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5130379-A | Anticholesterol agents and antidiabetic agents | PFIZER INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5036079-A | Anticholesterol | PFIZER INC. (US) | 1991-07-30 | — | — | US | disclosed |
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |