SCHEMBL9521974

SCHEMBL9521974

Nc1ccc(S)c(N)c1N

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.32
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
THRB P10828 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
LMNA P02545 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
BLM P54132 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9956575 0.97 CD44 (0.31) CD44
Hydrochloric Acid SCHEMBL9954791 0.97 CD44 (0.31) CD44
SCHEMBL10054269 0.87 MEN1 (0.33) MEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL7049662 0.83 MEN1 (0.31) MEN1KMT2AMAPT
SCHEMBL30884128 0.79 CYP3A4 (0.43) CD44MEN1KMT2ATDP1THRB
SCHEMBL135806 0.79 CYP3A4 (0.43) CD44MEN1KMT2ATDP1THRB
SCHEMBL10434472 0.79
SCHEMBL2316923 0.79 CD44 (0.31) CD44
Hydrochloric Acid SCHEMBL4938386 0.77
Hydrochloric Acid SCHEMBL11417611 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012085167-A1 METABOTROPIC GLUTAMATE RECEPTOR MODULATORS MERZ PHARMA GMBH & CO. KGAA (DE) 2012-06-28 WO claimed
WO-2012087182-A2 SUBSTITUTED METHYL AMINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS FOR THE PRODUCTION AND USE THEREOF АЛЛА ХЕМ, ЛЛС (US) 2012-06-28 WO claimed
WO-2012088184-A1 INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO claimed
EP-0408321-B1 TRANSITION METAL TRIS-DITHIOLENE AND RELATED COMPLEXES AS PRECURSORS TO ACTIVE CATALYSTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-04-14 EP claimed
WO-2012088182-A3 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-12-06 WO disclosed
WO-2012088184-A1 INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
WO-2012088190-A1 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
WO-2012088190-A1 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
WO-2012085167-A1 METABOTROPIC GLUTAMATE RECEPTOR MODULATORS MERZ PHARMA GMBH & CO. KGAA (DE) 2012-06-28 WO disclosed
WO-2012088182-A2 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
WO-2012088182-A2 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed