SCHEMBL9522435

SCHEMBL9522435

CON=C(C)C12CCN(CC1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.59
CHRM4 P08173 2/20 0.59
CHRM1 P11229 2/20 0.59
CHRM3 P20309 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL9523436 0.91 CHRM2 (0.51) CHRM2CHRM4CHRM1CHRM3
SCHEMBL9444163 0.88 CHRM2 (0.49) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8791499 0.81 CHRM2 (0.54) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8791504 0.81 CHRM2 (0.54) CHRM2CHRM4CHRM1CHRM3
SCHEMBL6627385 0.78 CHRM2 (0.57) CHRM2CHRM4CHRM1CHRM3
SCHEMBL6625862 0.78 CHRM2 (0.57) CHRM2CHRM4CHRM1CHRM3
SCHEMBL6626676 0.78 CHRM2 (0.57) CHRM2CHRM4CHRM1CHRM3
SCHEMBL6624592 0.74 CHRM2 (1.00) CHRM2CHRM4CHRM1CHRM3
SCHEMBL6628913 0.74 CHRM2 (1.00) CHRM2CHRM4CHRM1CHRM3
Oxalic Acid SCHEMBL8791381 0.74 CHRM2 (0.48) CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338723-B1 NOVEL COMPOUNDS BEECHAM GROUP PLC (GB) 1993-08-04 EP claimed
US-5110828-A Treatment or prophylaxis of dementia BEECHAM GROUP P.L.C. (GB) 1992-05-05 US claimed
EP-0338723-A1 Novel compounds BEECHAM GROUP PLC (GB) 1989-10-25 EP claimed