Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522383 | 0.87 | PDGFRB (0.61) | PDGFRBPDGFRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9525590 | 0.80 | PDGFRB (0.71) | PDGFRBPDGFRAKMT2AALDH1A1KDM4E | |
| SCHEMBL741209 | 0.80 | PDGFRB (0.58) | PDGFRBPDGFRAKMT2AMEN1PKM | |
| SCHEMBL9591517 | 0.79 | PDGFRB (0.53) | PDGFRBPDGFRAKMT2AMEN1POLB | |
| SCHEMBL14817808 | 0.77 | PDGFRB (0.55) | PDGFRBPDGFRAKMT2APOLBALDH1A1 | |
| SCHEMBL30994852 | 0.75 | PDGFRB (0.59) | PDGFRBPDGFRAKMT2AALDH1A1HPGD | |
| SCHEMBL22502477 | 0.75 | PDGFRB (0.59) | PDGFRBPDGFRAKMT2AALDH1A1HPGD | |
| SCHEMBL27390362 | 0.75 | KMT2A (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL6514324 | 0.74 | RXFP1 (0.53) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL25260588 | 0.74 | PDGFRB (0.53) | PDGFRBPDGFRAKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |