Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | PPARG | P37231 | 3/20 | 0.71 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.71 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.67 |
| ▸ | APEX1 | P27695 | 3/20 | 0.67 |
| ▸ | APAF1 | O14727 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.67 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.67 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204242 | 0.94 | NR1I2 (0.74) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9204227 | 0.94 | NR1I2 (0.74) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10382891 | 0.94 | NR1I2 (0.65) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10366779 | 0.93 | NR1I2 (0.73) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10384580 | 0.92 | TDP1 (0.71) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5679450 | 0.92 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9371771 | 0.92 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10761869 | 0.92 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10554693 | 0.92 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5679457 | 0.92 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249170-B1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4971963-A | BACTERICIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4921851-A | Cephem compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0333082-A2 | Cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-09-20 | — | — | EP | disclosed |
| US-4833134-A | ANTIBIOTICS, BACTERIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0256542-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1988-02-24 | — | — | EP | disclosed |
| EP-0249170-A2 | Cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-16 | — | — | EP | disclosed |