⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950910 | 0.91 | — | — | |
| SCHEMBL2421100 | 0.82 | — | — | |
| SCHEMBL8457309 | 0.69 | — | — | |
| SCHEMBL9049519 | 0.61 | CHRM2 (0.32) | — | |
| SCHEMBL9376959 | 0.60 | CHRM2 (0.34) | — | |
| SCHEMBL14699885 | 0.55 | — | — | |
| SCHEMBL5263192 | 0.53 | — | — | |
| SCHEMBL20220999 | 0.53 | — | — | |
| SCHEMBL11722589 | 0.53 | — | — | |
| SCHEMBL2362307 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | claimed |
| US-5110828-A | Treatment or prophylaxis of dementia | BEECHAM GROUP P.L.C. (GB) | 1992-05-05 | — | — | US | claimed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | claimed |
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5110828-A | Treatment or prophylaxis of dementia | BEECHAM GROUP P.L.C. (GB) | 1992-05-05 | — | — | US | disclosed |
| US-5091397-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0363085-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-04-11 | — | — | EP | disclosed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | disclosed |