Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 17/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522366 | 0.91 | PTAFR (0.54) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9674442 | 0.90 | PTAFR (0.68) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10412015 | 0.90 | PTAFR (0.67) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9522862 | 0.89 | PTAFR (0.52) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10410495 | 0.87 | PTAFR (0.70) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9040885 | 0.87 | PTAFR (0.62) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9041476 | 0.87 | PTAFR (0.62) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9040170 | 0.86 | PTAFR (0.63) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9039332 | 0.86 | PTAFR (0.63) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10410718 | 0.86 | PTAFR (0.58) | PTAFROPRK1PDE4DCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960770-A | Vasodilating agents, cardiovascular disorder | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-02 | — | — | US | claimed |
| EP-0315698-A1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-05-17 | — | — | EP | claimed |
| EP-0315698-B1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4960770-A | Vasodilating agents, cardiovascular disorder | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0315698-A1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |