Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523473 | 0.88 | NR1I2 (0.38) | CYP3A4CYP2D6NR1I2ALDH1A1MEN1 | |
| SCHEMBL13688008 | 0.85 | NR1I2 (0.52) | CYP3A4CYP2D6NR1I2ALDH1A1MEN1 | |
| SCHEMBL9522093 | 0.83 | CYP3A4 (0.42) | CYP3A4CYP2D6NR1I2ALDH1A1MEN1 | |
| SCHEMBL9200266 | 0.79 | NR1I2 (0.73) | CYP3A4CYP2D6NR1I2ALDH1A1MEN1 | |
| SCHEMBL9522035 | 0.79 | MAPT (0.35) | CYP3A4CYP2D6ALDH1A1MEN1KMT2A | |
| SCHEMBL13623370 | 0.75 | NR1I2 (0.61) | CYP3A4CYP2D6NR1I2L3MBTL1S1PR1 | |
| SCHEMBL9202945 | 0.75 | NR1I2 (0.67) | CYP3A4CYP2D6NR1I2ALDH1A1MEN1 | |
| SCHEMBL13623353 | 0.72 | NR1I2 (0.71) | CYP3A4CYP2D6NR1I2 | |
| SCHEMBL9210194 | 0.71 | NR1I2 (0.53) | CYP3A4CYP2D6NR1I2MEN1KMT2A | |
| SCHEMBL9520881 | 0.71 | PPARA (0.35) | CYP3A4CYP2D6NR1I2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |