Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290559 | 0.90 | MEN1 (0.58) | CNR2MEN1KMT2ADRD3DRD4 | |
| SCHEMBL2291058 | 0.90 | DRD4 (0.55) | CNR2DRD3DRD4 | |
| SCHEMBL2298962 | 0.90 | MEN1 (0.58) | CNR2MEN1KMT2ADRD3DRD4 | |
| SCHEMBL2294726 | 0.90 | CNR2 (0.49) | CNR2MEN1KMT2ADRD3DRD4 | |
| SCHEMBL497466 | 0.90 | CNR2 (0.49) | CNR2MEN1KMT2ADRD3DRD4 | |
| SCHEMBL4649659 | 0.90 | CNR2 (0.55) | CNR2MEN1KMT2ADRD3 | |
| SCHEMBL2294931 | 0.90 | DRD4 (0.55) | CNR2DRD3DRD4 | |
| SCHEMBL2291934 | 0.87 | DRD3 (0.52) | CNR2MEN1KMT2ADRD3DRD4 | |
| SCHEMBL2294553 | 0.87 | DRD3 (0.52) | CNR2MEN1KMT2ADRD3DRD4 | |
| SCHEMBL2295182 | 0.86 | HRH3 (0.57) | CNR2KMT2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507863-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | — | 1993-07-07 | — | — | EP | claimed |
| EP-0507863-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1992-10-14 | — | — | EP | claimed |
| WO-1991009594-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-07-11 | — | — | WO | claimed |