Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784760 | 0.85 | AR (0.62) | ARKDM4EUSP2ALDH1A1 | |
| SCHEMBL9635738 | 0.84 | AR (0.55) | ARMAOBMAOANPC1RAB9A | |
| SCHEMBL5842342 | 0.81 | AR (0.52) | ARMAOBMAOANPC1RAB9A | |
| SCHEMBL31753532 | 0.79 | MAOB (0.45) | MAOBMAOACA12CA9 | |
| SCHEMBL13367745 | 0.79 | AR (0.59) | ARNPC1RAB9AKDM4EUSP2 | |
| SCHEMBL1608900 | 0.76 | AR (0.69) | ARCA12CA9KDM4EUSP2 | |
| SCHEMBL9786397 | 0.74 | MAPT (0.50) | MAOBMAOACA12CA9NPC1 | |
| SCHEMBL19614570 | 0.74 | AR (0.54) | ARALDH1A1 | |
| SCHEMBL6288611 | 0.73 | MAOB (0.55) | ARMAOBMAOA | |
| SCHEMBL2133552 | 0.73 | TNF (0.49) | ARMAOBMAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |