Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080259 | 0.90 | EPHA2 (0.73) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9523387 | 0.85 | EPHA2 (0.43) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL5197287 | 0.85 | EPHA2 (0.80) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL4602293 | 0.85 | EPHA2 (0.80) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7849173 | 0.84 | EPHA2 (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9524135 | 0.84 | DPP4 (0.51) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9381255 | 0.84 | KMT2A (0.81) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL5197108 | 0.84 | KMT2A (0.81) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| Hydrochloric Acid SCHEMBL8130789 | 0.83 | KMT2A (0.79) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9523191 | 0.83 | EPHA2 (0.39) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357047-B1 | Spiro compounds | DAIICHI SEIYAKU CO (JP) | 1993-11-03 | — | — | EP | claimed |