SCHEMBL9523968

SCHEMBL9523968

Cc1nc2cnccc2n1-c1ccc(C(N)=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
DRD1 P21728 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7505146 0.88 HSD17B10 (0.59) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
SCHEMBL9384977 0.88 HSD17B10 (0.49) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
SCHEMBL9525676 0.86 HSD17B10 (0.48) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL9697856 0.85 MEN1 (0.45) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL9523368 0.85 MEN1 (0.45) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
SCHEMBL7497691 0.84 POLB (0.56) HSD17B10DRD1MEN1KMT2A
SCHEMBL9524668 0.84 HSD17B10 (0.55) HSD17B10SMN1; SMN2MEN1KMT2A
SCHEMBL9586997 0.82 DRD1 (0.46) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
SCHEMBL9559464 0.82 HSD17B10 (0.47) HSD17B10DRD1SMN1; SMN2MEN1KMT2A
SCHEMBL14000496 0.82 MAPK1 (0.64) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530207-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS Pfizer Limited (GB) 1993-03-10 EP disclosed
WO-1991017162-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS PFIZER LIMITED (GB) 1991-11-14 WO disclosed