Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775530 | 0.88 | KDM4E (0.74) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL1857925 | 0.86 | KDM4E (0.76) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9808640 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10514904 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10513004 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9370629 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10655445 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL7763708 | 0.82 | KDM4E (0.85) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10808537 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9381623 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357047-B1 | Spiro compounds | DAIICHI SEIYAKU CO (JP) | 1993-11-03 | — | — | EP | claimed |