Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524097 | 1.00 | KMT2A (0.66) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL9523424 | 0.94 | MAOB (0.61) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL17355377 | 0.94 | MAOB (0.61) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL5315888 | 0.94 | MAOB (0.61) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL15367534 | 0.94 | MAOB (0.61) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL9522518 | 0.87 | MAOB (0.66) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL9478343 | 0.87 | MAOB (0.73) | KMT2AMAOBMAOAMEN1PTGS2 | |
| SCHEMBL10744603 | 0.87 | KMT2A (0.64) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL10744598 | 0.87 | KMT2A (0.64) | KMT2AMAOBMAOABCHEMEN1 | |
| SCHEMBL16024199 | 0.87 | MAOB (0.61) | KMT2AMAOBMAOABCHECYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |