Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.70 |
| ▸ | CTSG | P08311 | 2/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | CTRC | Q99895 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524116 | 0.85 | ELANE (0.70) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL11453870 | 0.78 | ELANE (0.70) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL11772829 | 0.76 | ELANE (0.68) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL9524179 | 0.75 | ELANE (0.55) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL8498625 | 0.73 | KMT2A (0.64) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL4002616 | 0.72 | ELANE (0.61) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL11076806 | 0.72 | KMT2A (0.61) | ELANECTSGPRTN3NPSR1KMT2A | |
| SCHEMBL19923520 | 0.71 | ELANE (0.61) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL7833789 | 0.71 | ELANE (0.71) | ELANECTSGPRTN3F2PLG | |
| SCHEMBL17716272 | 0.71 | NPSR1 (0.63) | ELANECTSGPRTN3F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571400-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO.,LTD. (KR) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992012155-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO., LTD. (KR) | 1992-07-23 | — | — | WO | disclosed |