Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168685 | 0.87 | MEN1 (0.53) | RPS6KA5DRD1 | |
| SCHEMBL7774816 | 0.87 | DRD1 (0.49) | RPS6KA5DRD1 | |
| SCHEMBL10388437 | 0.83 | DRD1 (0.47) | RPS6KA5DRD1 | |
| SCHEMBL9525557 | 0.83 | MAPK1 (0.51) | RPS6KA5DRD1 | |
| SCHEMBL10054042 | 0.83 | DRD1 (0.53) | DRD1 | |
| SCHEMBL9526774 | 0.82 | PDPK1 (0.51) | RPS6KA5DRD1AKT1 | |
| SCHEMBL9332789 | 0.81 | KLKB1 (0.51) | DRD1 | |
| SCHEMBL9335272 | 0.81 | DRD1 (0.51) | DRD1 | |
| SCHEMBL540767 | 0.80 | MAPK1 (0.67) | RPS6KA5DRD1 | |
| SCHEMBL9049974 | 0.80 | GALR3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |