Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.82 |
| ▸ | CES2 | O00748 | 3/20 | 0.82 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.81 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.62 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.62 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.62 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.62 |
| ▸ | PTPRC | P08575 | 2/20 | 0.62 |
| ▸ | PTPRF | P10586 | 2/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.62 |
| ▸ | ACP1 | P24666 | 2/20 | 0.62 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.62 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Katonic Acid Methyl Ester SCHEMBL24212353 | 1.00 | CES1 (0.82) | CES1CES2ALOX5USP2PTPN1 | |
| Katonic Acid Methyl Ester SCHEMBL15513664 | 1.00 | CES1 (0.82) | CES1CES2ALOX5USP2PTPN1 | |
| Katonic Acid Methyl Ester SCHEMBL9525631 | 1.00 | CES1 (0.82) | CES1CES2ALOX5USP2PTPN1 | |
| SCHEMBL417930 | 0.90 | CES1 (0.77) | CES1CES2ALOX5USP2PTPN1 | |
| SCHEMBL1050528 | 0.90 | PTPN1 (0.78) | CES1CES2ALOX5USP2PTPN1 | |
| SCHEMBL24627172 | 0.90 | PTPN1 (0.78) | CES1CES2ALOX5USP2PTPN1 | |
| Katonic Acid SCHEMBL14071729 | 0.89 | CES1 (1.00) | CES1CES2ALOX5USP2PTPN1 | |
| Katonic Acid SCHEMBL8897742 | 0.89 | CES1 (1.00) | CES1CES2ALOX5USP2PTPN1 | |
| Katonic Acid SCHEMBL1785482 | 0.89 | CES1 (1.00) | CES1CES2ALOX5USP2PTPN1 | |
| Katonic Acid SCHEMBL13144259 | 0.89 | CES1 (1.00) | CES1CES2ALOX5USP2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272478-B1 | GLYCYRRHETIC ACID DERIVATIVES AND USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-4871740-A | ANTIULCER AGENT; REDUCTION OF SIDE EFFECTS FROM STEROIDS | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0272478-A1 | Glycyrrhetic acid derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |